

At Hamari Chemicals, we have the capability to conduct reduction
reactions of more than 30 tons a year. We have successfully synthesized
Lysinopril ester by an asymmetric Base reduction with Raney nickel.
Hamari also has extensive experience in reduction with DIBAH reagent
on the commercial level.
We have 10 autoclaves ranging in size from 10L to 1800L to provide
the capacity needed for your custom synthesis.
We have two specially designed autoclaves, one SS reactor that is
rated to
990 psi and another is a hastelloy reactor is rated to 140psi under
acidic conditions.
Hamari Chiral Technology
We develop the Hamari chiral technology such as an asymmetric transfer
hydrogenetion using chiral Ru-catalyst. We are producing some APIs
and intermediates by using our patented chiral technology. As for
the quality, we can achieve chemical purity of 99% and an optical
purity of 99%ee. In addition, we can eliminate Ru down several
ppb in final product.
Click the PDF file below to view more detailed information on our
Reduction manufacturing, including:
Reduction
PDF file
• Two specially designed autoclaves
• Homogeneous Asymmetric Hydrogenation
using Chiral Ru-catalyst
• Asymmetric Schiff Base Reduction
• Reduction with DIBAH on A Commercial Scale
• Horner-Emmons Reaction
• Reductive Amination
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