Drug DiscoveryDrug Design・Chemical Synthesis
Pre-Clinical Study・Investigational New DrugScale Up・Process Development・Analysis Development
Clinical StudyProcess Optimization・GMP Production・Stability Test・Method Validation・Method Validation・Process Validation
New Drug ApplicationPre-Approval Inspection・Regulatory Filings
Commercial ProductionActual Commercial Manufacture
Hamari Chemicals, Ltd. is collaborating with Professor Vadim A. Soloshonok to develop innovative synthetic process for unnatural amino acids. The ”Soloshonok-Hamari Ligand” is an ideal tool to produce various unnatural amino acids at high efficiency.
Using these ligands and readily available racemic/natural amino acids, a variety of tailor-made unnatural amino acids can be synthesized with high stereoselectivity by chiral interconversion and/or functionalization at the α-carbon position. These ligands do not racemize, and are easily recovered and recycled to permit cost-effective large scale manufacture.
This technology is the ultimate advanced approach for tailor-made amino acids.
|Download our Unnatural Amino Acid Product List|