論文・特許
事業を通して得られた知見や成果を社会に還元するため、学会発表、論文投稿、特許取得を行っています。
■最近の投稿論文・総説
Dynamic Thermodynamic Resolution of Unprotected Amino Acids Using Ni(II) Chiral 続きを読む...
Rapid and efficient syntheses of tryptophans using a continuous-flow quaternizat 続きを読む...
Aldol addition-cyclization reaction cascade on a platform of chiral Ni(II) compl 続きを読む...
Tailor-made amino acids in the design of small-molecule blockbuster drugs. Eur. 続きを読む...
浜理薬品とSoloshonok教授、Han教授の共著論文が、Symmetry 2021 Best Paper Awardsを受賞致しました。 Co 続きを読む...
Asymmetric synthesis of (S)-α-(octyl)glycine via alkylation of Ni(II) complex of 続きを読む...
含フッ素アミノ酸の医薬品及び候補化合物合成への応用 Applications of fluorine-containing amino acids for dr 続きを読む...
Tailor-made amino acid-derived pharmaceuticals approved by the FDA in 2019. Amin 続きを読む...
Michael addition reactions of chiral glycine Schiff base Ni(II)-complex with 1-( 続きを読む...
Asymmetric Synthesis of 4,4‐(Difluoro)glutamic Acid via Chiral Ni(II)‐Complexes 続きを読む...
■特許
- METHOD FOR PRODUCING PEPTIDE. WO2018/181679.
- METHOD FOR SYNTHESIZING OPTICALLY ACTIVE α-AMINO ACID USING CHIRAL METAL COMPLEX COMPRISING AXIALLY CHIRAL N-(2-ACYLARYL)-2-[5,7-DIHYDRO-6H-DIBENZO[c,e]AZEPIN-6-YL]ACETAMIDE COMPOUND AND AMINO ACID. WO2014188783.
- AXIAL-ASYMMETRIC N-(2-ACYLARYL)-2-[5, 7-DIHYDRO-6H-DIBENZO [C, E] AZEPINE-6-YL] ACETAMIDE COMPOUND AND CHIRALITY CONVERSION METHOD FOR [Alpha]-AMINO ACID USING SAME. WO2014098063.
- METHOD FOR PRODUCING OPTICALLY ACTIVE ALCOHOL. WO2013061999.
- METHOD FOR PRODUCING OPTICALLY ACTIVE TETRAHYDROQUINOLINE. WO2013011930.
- METHOD FOR PRODUCING FINE POWDER OF LOXOPROFEN SODIUM DIHYDRATE FOR PHARMACEUTICAL PREPARATIONS. WO2012137667.
- NOVEL DIHYDROTRIAZINE DERIVATIVE. WO2010024225.
- PROCESS FOR PRODUCTION OF ETHYNYLTHYMIDINE COMPOUND USING 5-METHYLURIDINE AS STARTING RAW MATERIAL. WO2009125841.
- METHOD FOR PURIFYING ETHYNYLTHYMIDINE COMPOUND. WO2009119785.
- METHOD FOR SYNTHESIZING L-ANSERINE. JP2005082571.
- NOVEL 2,4-DIAMINO-1,3,5-TRIAZINE DERIVATIVE. WO2004054989.
