論文・特許

事業を通して得られた知見や成果を社会に還元するため、学会発表、論文投稿、特許取得を行っています。

■最近の投稿論文・総説

Dynamic Thermodynamic Resolution of Unprotected Amino Acids Using Ni(II) Chiral 続きを読む...
Rapid and efficient syntheses of tryptophans using a continuous-flow quaternizat 続きを読む...
Aldol addition-cyclization reaction cascade on a platform of chiral Ni(II) compl 続きを読む...
Tailor-made amino acids in the design of small-molecule blockbuster drugs. Eur. 続きを読む...
浜理薬品とSoloshonok教授、Han教授の共著論文が、Symmetry 2021 Best Paper Awardsを受賞致しました。   Co 続きを読む...
Asymmetric synthesis of (S)-α-(octyl)glycine via alkylation of Ni(II) complex of 続きを読む...
含フッ素アミノ酸の医薬品及び候補化合物合成への応用 Applications of fluorine-containing amino acids for dr 続きを読む...
Tailor-made amino acid-derived pharmaceuticals approved by the FDA in 2019. Amin 続きを読む...
Michael addition reactions of chiral glycine Schiff base Ni(II)-complex with 1-( 続きを読む...
Asymmetric Synthesis of 4,4‐(Difluoro)glutamic Acid via Chiral Ni(II)‐Complexes 続きを読む...

■特許

  1. METHOD FOR PRODUCING PEPTIDE. WO2018/181679.
  2. METHOD FOR SYNTHESIZING OPTICALLY ACTIVE α-AMINO ACID USING CHIRAL METAL COMPLEX COMPRISING AXIALLY CHIRAL N-(2-ACYLARYL)-2-[5,7-DIHYDRO-6H-DIBENZO[c,e]AZEPIN-6-YL]ACETAMIDE COMPOUND AND AMINO ACID. WO2014188783.
  3. AXIAL-ASYMMETRIC N-(2-ACYLARYL)-2-[5, 7-DIHYDRO-6H-DIBENZO [C, E] AZEPINE-6-YL] ACETAMIDE COMPOUND AND CHIRALITY CONVERSION METHOD FOR [Alpha]-AMINO ACID USING SAME. WO2014098063.
  4. METHOD FOR PRODUCING OPTICALLY ACTIVE ALCOHOL. WO2013061999.
  5. METHOD FOR PRODUCING OPTICALLY ACTIVE TETRAHYDROQUINOLINE. WO2013011930.
  6. METHOD FOR PRODUCING FINE POWDER OF LOXOPROFEN SODIUM DIHYDRATE FOR PHARMACEUTICAL PREPARATIONS. WO2012137667.
  7. NOVEL DIHYDROTRIAZINE DERIVATIVE. WO2010024225.
  8. PROCESS FOR PRODUCTION OF ETHYNYLTHYMIDINE COMPOUND USING 5-METHYLURIDINE AS STARTING RAW MATERIAL. WO2009125841.
  9. METHOD FOR PURIFYING ETHYNYLTHYMIDINE COMPOUND. WO2009119785.
  10. METHOD FOR SYNTHESIZING L-ANSERINE. JP2005082571.
  11. NOVEL 2,4-DIAMINO-1,3,5-TRIAZINE DERIVATIVE. WO2004054989.